Severe acetabular dysplasia has been associated with premature hip OA. The impact of moderate acetabular dysplasia on the advancement of hip OA can be less clear. To assess the function of moderate acetabular dysplasia in the onset of hip OA, a study team in holland conducted a long-term research on 835 people age range 55 years and older. Their results, published in the March 2005 issue of Arthritis & Rheumatism, indicate acetabular dysplasia, even though assessed at a gentle degree, as a strong independent risk element for OA of the hip, within an elderly population even.And $3.3 million in Europe. Net revenues reported do not include $3.1 million related to the following items: Deferred revenue of $1.3 million in the U.S., representing Iclusig inventory on hand at our specialty pharmacy as of March 31, 2014 but not yet shipped to patients as of the ultimate end of the one fourth. Shipments of $1.8 million of Iclusig to sufferers in France during the first quarter , which will be recorded as revenue, when pricing and reimbursement negotiations in France are completed and the list cost is determined. We anticipate that this will occur around year-end 2014. Underlying affected individual demand during the first quarter was consistent with 2013 levels.