When CREB can be activated, it regulates the creation of a brain proteins known as neuropeptide Y. Low levels of energetic CREB or of neuropeptide Y correlate with symptoms of panic and excessive alcohol intake, the scientists showed in a prior study. In the present study, mice that had only one duplicate of the CREB gene – – healthy mice have two copies – – produced lower-than-normal degrees of the CREB protein, neuropeptide Y and another compound in the brain associated with alcohol drinking . The mice consumed about 50 % more alcoholic beverages than normal littermates and demonstrated higher baseline anxiety-like behaviors, as measured by a maze test.I was into sports. I did things involving sports.’ ‘Once they reviewed this information,’ he continued, ‘they got back to me and stated yes I do qualify for the doctorate level. At that time I paid them some cash.’ ‘How much money?’ I asked. ‘One thousand dollars roughly,’ Jake said. ‘The rates depended on whether you desired a full transcript or not really, and letters from professors.’ A full transcript? Actually? ‘Yes,’ Jake said. ‘They might create a fake transcript showing all the classes you ever got, with class descriptions, credit hours, your grades and everything. It was sent by them to me as part of the package.’ And how about the letters from professors? ‘They actually offered for a supplementary fee that they would write letters of recommendation from your professors, and that you could use those letters to get work interviews, or whatever you wanted to utilize them for.’ And how would all this endure under scrutiny if someone tried to confirm your academic history? ‘They sent me a letter that explained how to make use of all this to deceive companies.