The acceptance for submitting of the NDA indicates the FDA has established that the application is sufficiently complete to permit a substantive review. The application form will be subject to a standard review and can have a Prescription Medication User Fee Act date of November 5, 2014. The PDUFA date may be the goal time for the FDA to complete its overview of the NDA. David Dodd, CEO and President of Aeterna Zentaris, commented, The FDA's acceptance of this NDA submission is another significant milestone in our strategy to commercialize macimorelin acetate as the initial approved oral item for AGHD evaluation. We are finalizing our commercial plan for this exciting new item.Staying up All full night as an Owl It is not uncommon for extremely active ladies to take their work to bed. Once in a while, when you are loaded with work, it is fine. However, in the event that you often keep pushing your bedtime, that’s when the warning bell rings. Rest deprivation causes dark circles, sallow skin and also triggers a number of health disorders. It does not need to be perfect 8 hours of beauty sleep, but try to make sleep your priority. Your body shall be thankful for it. Exercising Too Much Too much of any good thing can be bad.